MSCbio and Skinmedience science-driven skin renewal technologies sales@mscbio.co.kr

SULPIQTriple Synergy Skin Conditioning

BEYOND PEELING.
AWAKEN THE SKIN.

SulfurNMNSpicule
SULPIQ open presentation box with vials, powder packs, and applicator

SULPIQ Professional Application Protocol

The SULPIQ concept

Beyond conventional
peeling care.

The next-generation skin conditioning platform that combines sulfur, NMN and spicule-based microchanneling.

Triple synergy

Three components.
One synergistic system.

Beyond Peeling: Bioactivation

The aesthetic market is moving beyond simple exfoliation. Clients now want skin that looks healthier, smoother, and more luminous.

SULPIQ is built around Epidermal Bioactivation — supporting the skin’s natural renewal process through controlled stimulation and active-ingredient support.

01
Signal Golden sulfur S8 ingredient emblem

Sulfur (S8)

Biochemical SignalingKeratinization Support
Reduction–Oxidation Balance

02
Energy Silver NMN ingredient emblem

NMN

Cellular Energy SupportNAD+ Precursor
Energy Metabolism

03
Trigger Rose-gold spicule ingredient emblem

Spicule

MicroneedlingIngredient Delivery

Five-stage SULPIQ process: spicule channeling, sulfur and NMN delivery, H2S signaling and NAD+ production, mitochondrial function support, and ECM optimization
Hands mixing a pale yellow preparation in a bowl with a spatula

The ritual

Freshly combined.
Precisely applied.

  1. 01

    Prepare

    Cleanse the skin and open one single-use powder container.

  2. 02

    Activate

    Add one vial to the powder and mix thoroughly just before use.

  3. 03

    Apply

    Spread the freshly prepared mixture evenly on the face.

  4. 04

    Finish

    Complete the treatment according to the detailed directions supplied with the product.

A new concept in dual-layer treatment

META-TDS
HydroLyDex + PLLA Thread

Dermal revitalization and structural support in one integrated approach. HydroLyDex supports the dermal layer while PLLA threads reinforce the subcutaneous layer.

Hyaluronic AcidL-LysineDextranPLLA
HydroLyDex device applying treatment across dermal and subcutaneous skin layers
Deep Hydration

Hyaluronic acid delivery for hydration support.

Structural Support

PLLA threads designed to support tissue fixation.

Skin Quality

Supports dermal condition and texture.

Safe & Effective

Designed for professional aesthetic use.

Dual-Layer Rejuvenation Concept

HydroLyDex supports dermal revitalization, while PLLA threads provide complementary structural support for integrated and long-lasting results.

Dual-layer diagram showing PLLA thread structural support in the subcutaneous layer and HydroLyDex revitalization in the dermal layer

How It Works

01

Subcutaneous Layer
PLLA Thread

Provides mechanical support and stimulates collagen production in the subcutaneous layer.

02

Dermal Layer
HydroLyDex

Delivers HA, L-Lysine and Dextran into the dermis to support hydration, skin quality and the ECM environment.

Integrated Effect

The dual-layer approach combines structural support with dermal revitalization to support overall skin quality.

Mechanism of Action

Day 0-3

Micro Bead Implantation & Instant Hydration

  • Needle-free delivery into the mid-dermis
  • HA swells for uniform microsphere dispersion
  • Immediate hydration and plumping
Day 3-14

M2 Macrophage Polarization

  • Hydrophilic surface supports a regenerative mode
  • Anti-inflammatory cytokine response
  • No giant cell or nodule risk indicated
Week 2-8

Fibroblast Activation & ECM Formation

  • Fibroblasts attach to microspheres
  • L-Lysine supports collagen activation
  • Collagen III and fibronectin synthesis
Month 2-6

ECM Completion & Biodegradation

  • Collagen remodeling completes
  • Dense, mature ECM network
  • Improved elasticity, texture and long-term results

Complementary Effects

Single Treatment vs. Dual-Layer Approach

Comparison of PLLA Thread only, HydroLyDex only and the combined Dual-Layer Approach

SULPIQ

Sulfur + NMN + Spicule

HydroLyDex + META-TDS + RYTIDE SHOT(PLLA3112)
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